5cqr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
==Dimerization of Elp1 is essential for Elongator complex assembly==
-
 
+
<StructureSection load='5cqr' size='340' side='right' caption='[[5cqr]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
-
The entry 5cqr is ON HOLD until Paper Publication
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5cqr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CQR FirstGlance]. <br>
-
Authors: Lin, Z., Xu, H., Li, F., Diao, W., Long, J., Shen, Y.
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cqs|5cqs]]</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cqr RCSB], [http://www.ebi.ac.uk/pdbsum/5cqr PDBsum]</span></td></tr>
-
Description: Dimerization of Elp1 is essential for Elongator complex assembly
+
</table>
-
[[Category: Unreleased Structures]]
+
== Disease ==
-
[[Category: Shen, Y]]
+
[[http://www.uniprot.org/uniprot/ELP1_HUMAN ELP1_HUMAN]] Familial dysautonomia. The disease is caused by mutations affecting the gene represented in this entry.
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/ELP1_HUMAN ELP1_HUMAN]] May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK). Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. Involved in neurogenesis (By similarity). Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (By similarity).[UniProtKB:Q7TT37]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Diao, W]]
[[Category: Li, F]]
[[Category: Li, F]]
-
[[Category: Xu, H]]
 
[[Category: Lin, Z]]
[[Category: Lin, Z]]
-
[[Category: Diao, W]]
 
[[Category: Long, J]]
[[Category: Long, J]]
 +
[[Category: Shen, Y]]
 +
[[Category: Xu, H]]
 +
[[Category: Dimerization]]
 +
[[Category: Elongator complex]]
 +
[[Category: Elp1 subunit]]
 +
[[Category: Familial dysautonomia]]
 +
[[Category: Protein binding]]

Revision as of 12:28, 20 August 2015

Dimerization of Elp1 is essential for Elongator complex assembly

5cqr, resolution 3.02Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5cqr"
Personal tools