5abj
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Structure of Coxsackievirus A16 in complex with GPP3== |
| - | + | <StructureSection load='5abj' size='340' side='right' caption='[[5abj]], [[Resolution|resolution]] 2.75Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5abj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coxsackievirus_a16 Coxsackievirus a16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ABJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ABJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=YM2:1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE'>YM2</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5abj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5abj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5abj RCSB], [http://www.ebi.ac.uk/pdbsum/5abj PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [ | + | [[http://www.uniprot.org/uniprot/I3W9E1_9ENTO I3W9E1_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Coxsackievirus a16]] |
| - | [[Category: Fry, E | + | [[Category: Colibus, L De]] |
| - | [[Category: | + | [[Category: Fry, E E]] |
| + | [[Category: Grimes, J M]] | ||
[[Category: Leyssen, P]] | [[Category: Leyssen, P]] | ||
| - | [[Category: Grimes, J.M]] | ||
| - | [[Category: Ren, J]] | ||
[[Category: Neyts, J]] | [[Category: Neyts, J]] | ||
[[Category: Puerstinger, G]] | [[Category: Puerstinger, G]] | ||
| - | [[Category: Stuart, D | + | [[Category: Rao, Z]] |
| + | [[Category: Ren, J]] | ||
| + | [[Category: Spyrou, J A.B]] | ||
| + | [[Category: Stuart, D I]] | ||
| + | [[Category: Tijsma, A]] | ||
| + | [[Category: Wang, X]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Virus]] | ||
Revision as of 11:22, 9 September 2015
Structure of Coxsackievirus A16 in complex with GPP3
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Categories: Coxsackievirus a16 | Colibus, L De | Fry, E E | Grimes, J M | Leyssen, P | Neyts, J | Puerstinger, G | Rao, Z | Ren, J | Spyrou, J A.B | Stuart, D I | Tijsma, A | Wang, X | Inhibitor | Virus
