5ac1
From Proteopedia
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| - | ''' | + | ==Sheep aldehyde dehydrogenase 1A1 with duocarmycin analog inhibitor== |
| - | + | <StructureSection load='5ac1' size='340' side='right' caption='[[5ac1]], [[Resolution|resolution]] 2.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ac1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AC1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K9P:1-[(1S)-1-METHYL-5-OXIDANYL-1,2-DIHYDROBENZO[E]INDOL-3-YL]HEXAN-1-ONE'>K9P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TXE:[[(2R,3S,4R,5R)-5-[(3R)-3-AMINOCARBONYL-3,4-DIHYDRO-2H-PYRIDIN-1-YL]-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHOXY-OXIDANIDYL-PHOSPHORYL]+[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+PHOSPHATE'>TXE</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5abm|5abm]], [[5ac0|5ac0]], [[5ac2|5ac2]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Retinal_dehydrogenase Retinal dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.36 1.2.1.36] </span></td></tr> | |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ac1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ac1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ac1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ac1 PDBsum]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/AL1A1_SHEEP AL1A1_SHEEP]] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Retinal dehydrogenase]] | ||
| + | [[Category: Blank, I D]] | ||
[[Category: Harteis, S]] | [[Category: Harteis, S]] | ||
| - | + | [[Category: Koch, M F]] | |
| - | [[Category: Koch, M | + | |
[[Category: Ochsenfeld, C]] | [[Category: Ochsenfeld, C]] | ||
| + | [[Category: Pestel, G]] | ||
| + | [[Category: Schneider, S]] | ||
| + | [[Category: Sieber, S A]] | ||
| + | [[Category: Tietze, L F]] | ||
| + | [[Category: Aldehyde dehydrogenase activity]] | ||
| + | [[Category: Oxidation-reduction process]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:37, 26 August 2015
Sheep aldehyde dehydrogenase 1A1 with duocarmycin analog inhibitor
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