5d5u
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of human Hsf1 with HSE DNA== |
| - | + | <StructureSection load='5d5u' size='340' side='right' caption='[[5d5u]], [[Resolution|resolution]] 2.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5u OCA], [http://pdbe.org/5d5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5u RCSB], [http://www.ebi.ac.uk/pdbsum/5d5u PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [[ | + | [[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bracher, A]] | [[Category: Bracher, A]] | ||
| + | [[Category: Double helix]] | ||
| + | [[Category: Helix-turn-helix]] | ||
| + | [[Category: Protein-dna complex]] | ||
| + | [[Category: Transcription-dna complex]] | ||
Revision as of 19:38, 30 December 2015
Crystal structure of human Hsf1 with HSE DNA
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