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5d5u

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'''Unreleased structure'''
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==Crystal structure of human Hsf1 with HSE DNA==
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<StructureSection load='5d5u' size='340' side='right' caption='[[5d5u]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
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The entry 5d5u is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5d5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D5U FirstGlance]. <br>
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Authors: Bracher, A.
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d5u OCA], [http://pdbe.org/5d5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d5u RCSB], [http://www.ebi.ac.uk/pdbsum/5d5u PDBsum]</span></td></tr>
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</table>
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Description:
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== Function ==
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[[Category: Unreleased Structures]]
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[[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bracher, A]]
[[Category: Bracher, A]]
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[[Category: Double helix]]
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[[Category: Helix-turn-helix]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription-dna complex]]

Revision as of 19:38, 30 December 2015

Crystal structure of human Hsf1 with HSE DNA

5d5u, resolution 2.91Å

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