5d9a
From Proteopedia
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| - | ''' | + | ==Influenza C Virus RNA-dependent RNA Polymerase - Space group P212121== |
| - | + | <StructureSection load='5d9a' size='340' side='right' caption='[[5d9a]], [[Resolution|resolution]] 4.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d9a]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D9A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D9A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d98|5d98]]</td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d9a OCA], [http://pdbe.org/5d9a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d9a RCSB], [http://www.ebi.ac.uk/pdbsum/5d9a PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PA_INCJH PA_INCJH]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication (By similarity). [[http://www.uniprot.org/uniprot/PB2_INCJH PB2_INCJH]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1 (By similarity). [[http://www.uniprot.org/uniprot/RDRP_INCJH RDRP_INCJH]] RNA-dependent RNA polymerase which is responsible for replication and transcription of virus segments. Binds the promoter sequence of the encapsidated viral RNA. Displays an endonuclease activity involved in cap-stealing. Cleaves cellular pre-mRNA to generate primers for viral transcription (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Bricogne, G]] | [[Category: Bricogne, G]] | ||
[[Category: Cusack, S]] | [[Category: Cusack, S]] | ||
| - | [[Category: | + | [[Category: Fodor, E]] |
| - | + | [[Category: Grimes, J M]] | |
| - | [[Category: Grimes, J | + | |
| - | + | ||
[[Category: Hengrung, N]] | [[Category: Hengrung, N]] | ||
| - | [[Category: Rambo, R | + | [[Category: Martin, I Serna]] |
| - | [[Category: Stuart, D | + | [[Category: Omari, K El]] |
| - | [[Category: | + | [[Category: Rambo, R P]] |
| + | [[Category: Stuart, D I]] | ||
| + | [[Category: Vonrhein, C]] | ||
| + | [[Category: Vreede, F T]] | ||
| + | [[Category: Influenza]] | ||
| + | [[Category: Influenza c virus]] | ||
| + | [[Category: Negative-strand virus]] | ||
| + | [[Category: Rna-dependent rna polymerase]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 05:34, 22 October 2015
Influenza C Virus RNA-dependent RNA Polymerase - Space group P212121
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