This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4oys
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405.== | ==CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405.== | ||
<StructureSection load='4oys' size='340' side='right' caption='[[4oys]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='4oys' size='340' side='right' caption='[[4oys]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4oys]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OYS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OYS FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4oys]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OYS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OYS FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1TT:(8S)-9-[(5-CHLORANYLPYRIDIN-3-YL)METHYL]-2-[(3R)-3-METHYLMORPHOLIN-4-YL]-8-(TRIFLUOROMETHYL)-6,7,8,9A-TETRAHYDRO-3H-PYRIMIDO[1,2-A]PYRIMIDIN-4-ONE'>1TT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1TT:(8S)-9-[(5-CHLORANYLPYRIDIN-3-YL)METHYL]-2-[(3R)-3-METHYLMORPHOLIN-4-YL]-8-(TRIFLUOROMETHYL)-6,7,8,9A-TETRAHYDRO-3H-PYRIMIDO[1,2-A]PYRIMIDIN-4-ONE'>1TT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIK3C3,VPS34 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_3-kinase Phosphatidylinositol 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.137 2.7.1.137] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_3-kinase Phosphatidylinositol 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.137 2.7.1.137] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oys OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oys RCSB], [http://www.ebi.ac.uk/pdbsum/4oys PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oys OCA], [http://pdbe.org/4oys PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oys RCSB], [http://www.ebi.ac.uk/pdbsum/4oys PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oys ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 17: | Line 19: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4oys" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 24: | Line 27: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Phosphatidylinositol 3-kinase]] | [[Category: Phosphatidylinositol 3-kinase]] | ||
[[Category: Marquette, J p]] | [[Category: Marquette, J p]] | ||
[[Category: Mathieu, M]] | [[Category: Mathieu, M]] | ||
[[Category: Lipid kinase]] | [[Category: Lipid kinase]] | ||
Revision as of 06:08, 6 June 2018
CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405.
| |||||||||||
