NADP-dependent malic enzyme

Best example is 3wja

Molecule NADP-dependent malic enzyme, also known as NADP-ME, NADP-dependent malic enzyme and Malic enzyme 1.

Function

electron carrier activity
NADP binding
ADP binding
oxaloacetate decarboxylase activity
NAD binding
metal ion binding
oxidoreductase activity
malate dehydrogenase (decarboxylating) (NADP+) activity
manganese ion binding
malate dehydrogenase (decarboxylating) (NAD+) activity
malic enzyme activity

Disease

Relevance

Structural highlights

Biological process

Is involved in the following biological processes:
malate metabolic process
oxidation-reduction process
response to carbohydrate
response to hormone
carbohydrate metabolic process
protein tetramerization
regulation of NADP metabolic process
NADP biosynthetic process
small molecule metabolic process
cellular lipid metabolic process

In structures

NADP-dependent malic enzyme is found in 3 PDB entries
Homo sapiens (2 PDB entries):
3wja : experimental method: X-ray diffraction, resolution: 2.548
2aw5 : experimental method: X-ray diffraction, resolution: 2.5
Columba livia (1 PDB entries):
1gq2 : experimental method: X-ray diffraction, resolution: 2.5

PDBe Citation Component