1a8g
From Proteopedia
(Difference between revisions)
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==HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910== | ==HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910== | ||
<StructureSection load='1a8g' size='340' side='right' caption='[[1a8g]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1a8g' size='340' side='right' caption='[[1a8g]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1a8g]] is a 2 chain structure | + | <table><tr><td colspan='2'>[[1a8g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A8G FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2Z4:BENZYL+[(1R)-1-({(1S,2S,3S)-1-BENZYL-2-HYDROXY-4-({(1S)-1-[(2-HYDROXY-4-METHOXYBENZYL)CARBAMOYL]-2-METHYLPROPYL}AMINO)-3-[(4-METHOXYBENZYL)AMINO]-4-OXOBUTYL}CARBAMOYL)-2,2-DIMETHYLPROPYL]CARBAMATE'>2Z4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2Z4:BENZYL+[(1R)-1-({(1S,2S,3S)-1-BENZYL-2-HYDROXY-4-({(1S)-1-[(2-HYDROXY-4-METHOXYBENZYL)CARBAMOYL]-2-METHYLPROPYL}AMINO)-3-[(4-METHOXYBENZYL)AMINO]-4-OXOBUTYL}CARBAMOYL)-2,2-DIMETHYLPROPYL]CARBAMATE'>2Z4</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a8g OCA], [http://pdbe.org/1a8g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a8g RCSB], [http://www.ebi.ac.uk/pdbsum/1a8g PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a8g OCA], [http://pdbe.org/1a8g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1a8g RCSB], [http://www.ebi.ac.uk/pdbsum/1a8g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1a8g ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a8g ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
Revision as of 09:12, 9 August 2017
HIV-1 PROTEASE IN COMPLEX WITH SDZ283-910
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