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2amt
From Proteopedia
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|PDB= 2amt |SIZE=350|CAPTION= <scene name='initialview01'>2amt</scene>, resolution 2.30Å | |PDB= 2amt |SIZE=350|CAPTION= <scene name='initialview01'>2amt</scene>, resolution 2.30Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=1AA:5'-O-[({[(2-{[(2-AMINOPHENYL)CARBONYL]OXY}ETHYL)OXY]PHOSPHINATO}OXY)PHOSPHINATO]CYTIDINE'>1AA</scene>, <scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span> |
|GENE= ispF, mecS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]) | |GENE= ispF, mecS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1gx1|1GX1]], [[1knj|1KNJ]], [[1u3p|1U3P]], [[2ao4|2AO4]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2amt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2amt OCA], [http://www.ebi.ac.uk/pdbsum/2amt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2amt RCSB]</span> | ||
}} | }} | ||
| Line 22: | Line 25: | ||
[[Category: Hunter, W N.]] | [[Category: Hunter, W N.]] | ||
[[Category: Ramsden, N L.]] | [[Category: Ramsden, N L.]] | ||
| - | [[Category: 1AA]] | ||
| - | [[Category: GPP]] | ||
| - | [[Category: ZN]] | ||
[[Category: isoprene biosynthesis]] | [[Category: isoprene biosynthesis]] | ||
[[Category: isoprenoid]] | [[Category: isoprenoid]] | ||
[[Category: lyase]] | [[Category: lyase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:54:43 2008'' |
Revision as of 22:54, 30 March 2008
| |||||||
| , resolution 2.30Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | ispF, mecS (Escherichia coli) | ||||||
| Activity: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12 | ||||||
| Related: | 1GX1, 1KNJ, 1U3P, 2AO4
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of 2C-Methyl-D-Erythritol 2,4-Clycodiphosphate Synthase complexed with a CDP derived fluorescent inhibitor
About this Structure
2AMT is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111
Page seeded by OCA on Mon Mar 31 01:54:43 2008
