This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jh8
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2jh8 |SIZE=350|CAPTION= <scene name='initialview01'>2jh8</scene>, resolution 3.22Å | |PDB= 2jh8 |SIZE=350|CAPTION= <scene name='initialview01'>2jh8</scene>, resolution 3.22Å | ||
|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | |SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene> | ||
| - | |LIGAND= <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE'>M7G | + | |LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE'>M7G</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jh8 OCA], [http://www.ebi.ac.uk/pdbsum/2jh8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jh8 RCSB]</span> | ||
}} | }} | ||
| Line 26: | Line 29: | ||
[[Category: Stuart, D I.]] | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
| - | [[Category: GUN]] | ||
| - | [[Category: M7G]] | ||
[[Category: core protein]] | [[Category: core protein]] | ||
[[Category: guanylyltransferase]] | [[Category: guanylyltransferase]] | ||
| Line 35: | Line 36: | ||
[[Category: virion protein]] | [[Category: virion protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:09 2008'' |
Revision as of 00:58, 31 March 2008
| |||||||
| , resolution 3.22Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
Overview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
About this Structure
2JH8 is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.
Reference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
Page seeded by OCA on Mon Mar 31 03:58:09 2008
