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2pzf
From Proteopedia
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|PDB= 2pzf |SIZE=350|CAPTION= <scene name='initialview01'>2pzf</scene>, resolution 2.000Å | |PDB= 2pzf |SIZE=350|CAPTION= <scene name='initialview01'>2pzf</scene>, resolution 2.000Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1xmi|1XMI]], [[1xmj|1XMJ]], [[2bb0|2BB0]], [[2bbs|2BBS]], [[2bbt|2BBT]], [[1r0z|1R0Z]], [[1r10|1R10]], [[2ixe|2IXE]], [[1l2t|1L2T]], [[1q12|1Q12]], [[1xef|1XEF]], [[2hyd|2HYD]], [[2pze|2PZE]], [[2pzg|2PZG]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzf OCA], [http://www.ebi.ac.uk/pdbsum/2pzf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pzf RCSB]</span> | ||
}} | }} | ||
'''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508''' | '''Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Congenital bilateral absence of vas deferens OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Cystic fibrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Hypertrypsinemia, neonatal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Pancreatitis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Sweat chloride elevation without CF OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Wasserman, S R.]] | [[Category: Wasserman, S R.]] | ||
[[Category: Zhao, X.]] | [[Category: Zhao, X.]] | ||
| - | [[Category: ATP]] | ||
| - | [[Category: MG]] | ||
[[Category: abc transporter]] | [[Category: abc transporter]] | ||
[[Category: cftr]] | [[Category: cftr]] | ||
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[[Category: nbd]] | [[Category: nbd]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:44 2008'' |
Revision as of 01:42, 31 March 2008
| |||||||
| , resolution 2.000Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | CFTR, ABCC7 (Homo sapiens) | ||||||
| Related: | 1XMI, 1XMJ, 2BB0, 2BBS, 2BBT, 1R0Z, 1R10, 2IXE, 1L2T, 1Q12, 1XEF, 2HYD, 2PZE, 2PZG
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508
About this Structure
2PZF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:42:44 2008
Categories: Homo sapiens | Single protein | Atwell, S. | Conners, K. | Emtage, S. | Gheyi, T. | Glenn, N R. | Hendle, J. | Lewis, H A. | Lu, F. | Rodgers, L A. | Romero, R. | Sauder, J M. | Smith, D. | Tien, H. | Wasserman, S R. | Zhao, X. | Abc transporter | Cftr | F508 | Hydrolase | Nbd
