2vf0

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|PDB= 2vf0 |SIZE=350|CAPTION= <scene name='initialview01'>2vf0</scene>, resolution 3.00&Aring;
|PDB= 2vf0 |SIZE=350|CAPTION= <scene name='initialview01'>2vf0</scene>, resolution 3.00&Aring;
|SITE= <scene name='pdbsite=AC1:Ndu+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:F89+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Ndu+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:F89+Binding+Site+For+Chain+B'>AC4</scene> and <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+B'>AC5</scene>
|SITE= <scene name='pdbsite=AC1:Ndu+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:F89+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Ndu+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:F89+Binding+Site+For+Chain+B'>AC4</scene> and <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+B'>AC5</scene>
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDU:2&#39;-DEOXY-5-NITROURIDINE+5&#39;-MONOPHOSPHATE'>NDU</scene> and <scene name='pdbligand=F89:S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID'>F89</scene>
+
|LIGAND= <scene name='pdbligand=CXM:N-CARBOXYMETHIONINE'>CXM</scene>, <scene name='pdbligand=F89:S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC+ACID'>F89</scene>, <scene name='pdbligand=NDU:2&#39;-DEOXY-5-NITROURIDINE+5&#39;-MONOPHOSPHATE'>NDU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span>
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=[[1jg0|1JG0]], [[1bid|1BID]], [[1jtu|1JTU]], [[1ddu|1DDU]], [[1bjg|1BJG]], [[1axw|1AXW]], [[2ftq|2FTQ]], [[1syn|1SYN]], [[1tsd|1TSD]], [[1ffl|1FFL]], [[1bq1|1BQ1]], [[2kce|2KCE]], [[1evf|1EVF]], [[2ftn|2FTN]], [[1dna|1DNA]], [[1kce|1KCE]], [[1jtq|1JTQ]], [[1f4g|1F4G]], [[1f4f|1F4F]], [[1tjs|1TJS]], [[1fwm|1FWM]], [[1an5|1AN5]], [[1f4c|1F4C]], [[1kzj|1KZJ]], [[1trg|1TRG]], [[2bbq|2BBQ]], [[2g8o|2G8O]], [[1tys|1TYS]], [[1nce|1NCE]], [[1jut|1JUT]], [[1tlc|1TLC]], [[2g8x|2G8X]], [[1evg|1EVG]], [[1qqq|1QQQ]], [[1ev8|1EV8]], [[1tls|1TLS]], [[1f4b|1F4B]], [[1zpr|1ZPR]], [[2fto|2FTO]], [[1kzi|1KZI]], [[1f4e|1F4E]], [[1bdu|1BDU]], [[3tms|3TMS]], [[2a9w|2A9W]], [[1tdu|1TDU]], [[2g8m|2G8M]], [[1aob|1AOB]], [[1bq2|1BQ2]], [[1aiq|1AIQ]], [[1f4d|1F4D]], [[1ev5|1EV5]], [[1ajm|1AJM]], [[2tsc|2TSC]], [[1tsn|1TSN]], [[3b5b|3B5B]], [[2vet|2VET]]
 +
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vf0 OCA], [http://www.ebi.ac.uk/pdbsum/2vf0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2vf0 RCSB]</span>
}}
}}
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[[Category: Montfort, W R.]]
[[Category: Montfort, W R.]]
[[Category: Sotelo-Mundo, R R.]]
[[Category: Sotelo-Mundo, R R.]]
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[[Category: F89]]
 
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[[Category: NDU]]
 
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[[Category: SO4]]
 
[[Category: 5-no2-dump]]
[[Category: 5-no2-dump]]
[[Category: antifolate binding]]
[[Category: antifolate binding]]
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[[Category: translation regulation]]
[[Category: translation regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 15:54:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:11:28 2008''

Revision as of 02:11, 31 March 2008


PDB ID 2vf0

Drag the structure with the mouse to rotate
, resolution 3.00Å
Sites: , , , and
Ligands: , , ,
Activity: Thymidylate synthase, with EC number 2.1.1.45
Related: 1JG0, 1BID, 1JTU, 1DDU, 1BJG, 1AXW, 2FTQ, 1SYN, 1TSD, 1FFL, 1BQ1, 2KCE, 1EVF, 2FTN, 1DNA, 1KCE, 1JTQ, 1F4G, 1F4F, 1TJS, 1FWM, 1AN5, 1F4C, 1KZJ, 1TRG, 2BBQ, 2G8O, 1TYS, 1NCE, 1JUT, 1TLC, 2G8X, 1EVG, 1QQQ, 1EV8, 1TLS, 1F4B, 1ZPR, 2FTO, 1KZI, 1F4E, 1BDU, 3TMS, 2A9W, 1TDU, 2G8M, 1AOB, 1BQ2, 1AIQ, 1F4D, 1EV5, 1AJM, 2TSC, 1TSN, 3B5B, 2VET


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH 5NO2DUMP AND BW1843U89


About this Structure

2VF0 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 05:11:28 2008

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