3c6k
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
|PDB= 3c6k |SIZE=350|CAPTION= <scene name='initialview01'>3c6k</scene>, resolution 1.95Å | |PDB= 3c6k |SIZE=350|CAPTION= <scene name='initialview01'>3c6k</scene>, resolution 1.95Å | ||
|SITE= <scene name='pdbsite=AC1:Spd+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spd+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spd+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spd+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene> | |SITE= <scene name='pdbsite=AC1:Spd+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spd+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spd+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spd+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene> | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=MTA:5'-DEOXY-5'-METHYLTHIOADENOSINE'>MTA</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22] </span> |
|GENE= SMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= SMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[3c6m|3C6M]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c6k OCA], [http://www.ebi.ac.uk/pdbsum/3c6k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c6k RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine''' | '''Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine''' | ||
| + | |||
| + | ==Disease== | ||
| + | Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300105 300105]], Smith-Magenis syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607642 607642]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 29: | Line 35: | ||
[[Category: Wu, H.]] | [[Category: Wu, H.]] | ||
[[Category: Zeng, H.]] | [[Category: Zeng, H.]] | ||
| - | [[Category: MTA]] | ||
| - | [[Category: SPD]] | ||
[[Category: phosphoprotein]] | [[Category: phosphoprotein]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
| Line 38: | Line 42: | ||
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:30:54 2008'' |
Revision as of 02:30, 31 March 2008
| |||||||
| , resolution 1.95Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | , , , , , , and | ||||||
| Ligands: | , | ||||||
| Gene: | SMS (Homo sapiens) | ||||||
| Activity: | Spermine synthase, with EC number 2.5.1.22 | ||||||
| Related: | 3C6M
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine
Disease
Known disease associated with this structure: Mental retardation, X-linked, Snyder-Robinson type OMIM:[300105], Smith-Magenis syndrome OMIM:[607642]
About this Structure
3C6K is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2QFM. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:30:54 2008
Categories: Homo sapiens | Single protein | Spermine synthase | Arrowsmith, C H. | Bochkarev, A. | Edwards, A M. | Loppnau, P. | Min, J. | Pegg, A E. | Plotnikov, A N. | SGC, Structural Genomics Consortium. | Sundstrom, M. | Weigelt, J. | Wu, H. | Zeng, H. | Phosphoprotein | Sgc | Spermidine aminopropyltransferase | Spmsy | Structural genomic | Structural genomics consortium
