1goe

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==MONITORING THE STRUCTURAL CONSEQUENCES OF PHE12-->D-PHE12 AND LEU15-->AIB15 SUBSTITUTION IN H/R CORTICOTROPIN RELEASING HORMONE: IMPLICATIONS FOR DESIGN OF CRH ANTAGONISTS.==
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==Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.==
<StructureSection load='1goe' size='340' side='right' caption='[[1goe]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
<StructureSection load='1goe' size='340' side='right' caption='[[1goe]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1goe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1goe OCA], [http://pdbe.org/1goe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1goe RCSB], [http://www.ebi.ac.uk/pdbsum/1goe PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1goe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1goe OCA], [http://pdbe.org/1goe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1goe RCSB], [http://www.ebi.ac.uk/pdbsum/1goe PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CRF_HUMAN CRF_HUMAN]] This hormone from hypothalamus regulates the release of corticotropin from pituitary gland.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 23:47, 21 October 2015

Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.

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