This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2k8r
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Solution structure of human acidic fibroblast growth factor in complex with anti-angiogenic drug inositol hexaphosphate (IP6)== | ==Solution structure of human acidic fibroblast growth factor in complex with anti-angiogenic drug inositol hexaphosphate (IP6)== | ||
<StructureSection load='2k8r' size='340' side='right' caption='[[2k8r]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2k8r' size='340' side='right' caption='[[2k8r]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hFGF-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hFGF-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k8r OCA], [http://pdbe.org/2k8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k8r RCSB], [http://www.ebi.ac.uk/pdbsum/2k8r PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k8r OCA], [http://pdbe.org/2k8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k8r RCSB], [http://www.ebi.ac.uk/pdbsum/2k8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k8r ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 13: | Line 14: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/2k8r_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/2k8r_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k8r ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| Line 30: | Line 31: | ||
[[Category: Kumar, S M]] | [[Category: Kumar, S M]] | ||
[[Category: Mohan, S K]] | [[Category: Mohan, S K]] | ||
| + | [[Category: Acetylation]] | ||
[[Category: Acidic fibroblast growth factor]] | [[Category: Acidic fibroblast growth factor]] | ||
[[Category: Angiogenesis]] | [[Category: Angiogenesis]] | ||
| Line 38: | Line 40: | ||
[[Category: Hormone]] | [[Category: Hormone]] | ||
[[Category: Mitogen]] | [[Category: Mitogen]] | ||
| + | [[Category: Polymorphism]] | ||
Revision as of 10:26, 18 July 2018
Solution structure of human acidic fibroblast growth factor in complex with anti-angiogenic drug inositol hexaphosphate (IP6)
| |||||||||||

