2c9l
From Proteopedia
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+ | ==Structure of the Epstein-Barr virus ZEBRA protein== | ||
<StructureSection load='2c9l' size='340' side='right' caption='[[2c9l]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='2c9l' size='340' side='right' caption='[[2c9l]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c9l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ebvg Ebvg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C9L FirstGlance]. <br> | <table><tr><td colspan='2'>[[2c9l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ebvg Ebvg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C9L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C9L FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zsd|1zsd]], [[2axf|2axf]], [[2axg|2axg]], [[2c9n|2c9n]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zsd|1zsd]], [[2axf|2axf]], [[2axg|2axg]], [[2c9n|2c9n]]</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c9l OCA], [http://pdbe.org/2c9l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c9l RCSB], [http://www.ebi.ac.uk/pdbsum/2c9l PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c9l OCA], [http://pdbe.org/2c9l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c9l RCSB], [http://www.ebi.ac.uk/pdbsum/2c9l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c9l ProSAT]</span></td></tr> |
</table> | </table> | ||
- | == Function == | ||
- | [[http://www.uniprot.org/uniprot/BZLF1_EBVB9 BZLF1_EBVB9]] Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1).<ref>PMID:2157874</ref> <ref>PMID:1847997</ref> <ref>PMID:8404860</ref> <ref>PMID:17079287</ref> <ref>PMID:19144704</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == |
Revision as of 08:36, 23 May 2018
Structure of the Epstein-Barr virus ZEBRA protein
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