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1zgc
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex With an (RS)-Tacrine(10)-Hupyridone Inhibitor.== | ==Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex With an (RS)-Tacrine(10)-Hupyridone Inhibitor.== | ||
<StructureSection load='1zgc' size='340' side='right' caption='[[1zgc]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1zgc' size='340' side='right' caption='[[1zgc]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zgb|1zgb]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zgb|1zgb]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zgc OCA], [http://pdbe.org/1zgc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zgc RCSB], [http://www.ebi.ac.uk/pdbsum/1zgc PDBsum], [http://www.topsan.org/Proteins/ISPC/1zgc TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zgc OCA], [http://pdbe.org/1zgc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zgc RCSB], [http://www.ebi.ac.uk/pdbsum/1zgc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zgc ProSAT], [http://www.topsan.org/Proteins/ISPC/1zgc TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zg/1zgc_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zg/1zgc_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zgc ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1zgc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1zgc" style="background-color:#fffaf0;"></div> | ||
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| - | ==See Also== | ||
| - | *[[AChE inhibitors and substrates|AChE inhibitors and substrates]] | ||
| - | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
| - | *[[Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor|Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor]] | ||
| - | *[[User:Dawn M. Wong|User:Dawn M. Wong]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 08:55, 2 May 2018
Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex With an (RS)-Tacrine(10)-Hupyridone Inhibitor.
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Categories: Acetylcholinesterase | Torpedo californica | Carlier, P R | Greenblatt, H M | Haviv, H | ISPC, Israel Structural Proteomics Center | Pang, Y P | Silman, I | Sussman, J L | Wong, D M | Enantiomeric selectivity | Hydrolase | Protein-inhibitor complex | Serine-hydrolase | Structural genomic
