2jav
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Human Kinase with pyrrole-indolinone ligand== | ||
<StructureSection load='2jav' size='340' side='right' caption='[[2jav]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2jav' size='340' side='right' caption='[[2jav]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5Z5:5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>5Z5</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5Z5:5-[(Z)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>5Z5</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cl1|2cl1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cl1|2cl1]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jav OCA], [http://pdbe.org/2jav PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jav RCSB], [http://www.ebi.ac.uk/pdbsum/2jav PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jav OCA], [http://pdbe.org/2jav PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jav RCSB], [http://www.ebi.ac.uk/pdbsum/2jav PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jav ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jav_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jav_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jav ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2jav" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2jav" style="background-color:#fffaf0;"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Das, S]] | [[Category: Das, S]] | ||
[[Category: Debreczeni, J E]] | [[Category: Debreczeni, J E]] | ||
| - | [[Category: Delft, F | + | [[Category: Delft, F von]] |
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Fedorov, O]] | [[Category: Fedorov, O]] | ||
Revision as of 18:53, 24 January 2018
Human Kinase with pyrrole-indolinone ligand
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Categories: Human | Arrowsmith, C H | Bray, J | Das, S | Debreczeni, J E | Delft, F von | Edwards, A | Fedorov, O | Gorrec, F | Knapp, S | Papagrigoriou, E | Pike, A C.W | Rellos, P | Sundstrom, M | Turnbull, A P | Weigelt, J | Atp-binding | Cell cycle | Cell division | Kinase | Magnesium | Meiosis | Metal-binding | Mitosis | Nuclear protein | Nucleotide-binding | Phosphorylation | Serine/threonine protein kinase | Serine/threonine-protein kinase | Transferase
