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1nqc
From Proteopedia
(Difference between revisions)
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==Crystal structures of Cathepsin S inhibitor complexes== | ==Crystal structures of Cathepsin S inhibitor complexes== | ||
<StructureSection load='1nqc' size='340' side='right' caption='[[1nqc]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='1nqc' size='340' side='right' caption='[[1nqc]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1nqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1nqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NQC FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C4P:N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE'>C4P</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C4P:N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE'>C4P</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1npz|1npz]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1npz|1npz]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nqc OCA], [http://pdbe.org/1nqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nqc RCSB], [http://www.ebi.ac.uk/pdbsum/1nqc PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nqc OCA], [http://pdbe.org/1nqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nqc RCSB], [http://www.ebi.ac.uk/pdbsum/1nqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nqc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nqc ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1nqc" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1nqc" style="background-color:#fffaf0;"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Cathepsin|Cathepsin]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Ammirati, M]] | [[Category: Ammirati, M]] | ||
[[Category: Cygler, M]] | [[Category: Cygler, M]] | ||
Revision as of 09:42, 12 October 2017
Crystal structures of Cathepsin S inhibitor complexes
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Categories: Cathepsin S | Human | Ammirati, M | Cygler, M | Danley, D E | Griffor, M C | Kamath, A V | Laird, E R | Menard, R | Pauly, T A | Rath, V L | Sivaraman, J | Sulea, T | Wang, I K | Antigen presentation | Binding specificity | Cysteine protease | Hydrolase | Inhibitor complex | Structural plasticity | Structure-based design
