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4rz8
From Proteopedia
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==Crystal structure of HIV-1 gp120 core in complex with NBD-11021, a small molecule CD4-antagonist== | ==Crystal structure of HIV-1 gp120 core in complex with NBD-11021, a small molecule CD4-antagonist== | ||
<StructureSection load='4rz8' size='340' side='right' caption='[[4rz8]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4rz8' size='340' side='right' caption='[[4rz8]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4rz8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZ8 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4rz8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZ8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZM:5-(4-CHLOROPHENYL)-N-{(S)-[5-(HYDROXYMETHYL)-4-METHYL-1,3-THIAZOL-2-YL][(2R)-PIPERIDIN-2-YL]METHYL}-1H-PYRROLE-2-CARBOXAMIDE'>3ZM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZM:5-(4-CHLOROPHENYL)-N-{(S)-[5-(HYDROXYMETHYL)-4-METHYL-1,3-THIAZOL-2-YL][(2R)-PIPERIDIN-2-YL]METHYL}-1H-PYRROLE-2-CARBOXAMIDE'>3ZM</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rz8 OCA], [http://pdbe.org/4rz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rz8 RCSB], [http://www.ebi.ac.uk/pdbsum/4rz8 PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">env ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rz8 OCA], [http://pdbe.org/4rz8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rz8 RCSB], [http://www.ebi.ac.uk/pdbsum/4rz8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rz8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
Revision as of 02:59, 16 November 2017
Crystal structure of HIV-1 gp120 core in complex with NBD-11021, a small molecule CD4-antagonist
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