This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5aqe
From Proteopedia
(Difference between revisions)
m (Protected "5aqe" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | ''' | + | ==Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase== |
| - | + | <StructureSection load='5aqe' size='340' side='right' caption='[[5aqe]], [[Resolution|resolution]] 1.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5aqe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AQE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VOD:(4-VINYLPHENYL)METHANESULFONIC+ACID'>VOD</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aqe OCA], [http://pdbe.org/5aqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aqe RCSB], [http://www.ebi.ac.uk/pdbsum/5aqe PDBsum]</span></td></tr> | |
| - | [ | + | </table> |
| - | [ | + | == Function == |
| - | [ | + | [[http://www.uniprot.org/uniprot/SUBS_BACLE SUBS_BACLE]] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. |
| - | [ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Subtilisin]] |
| - | [[Category: | + | [[Category: Davies, G J]] |
| - | [[Category: | + | [[Category: Davis, B G]] |
[[Category: Diaz-Rodriguez, A]] | [[Category: Diaz-Rodriguez, A]] | ||
[[Category: Mcdonough, M]] | [[Category: Mcdonough, M]] | ||
| + | [[Category: Offen, W A]] | ||
| + | [[Category: Palm-Espling, M E]] | ||
| + | [[Category: Pordea, A]] | ||
| + | [[Category: Sharma, M]] | ||
| + | [[Category: Wormald, M R]] | ||
| + | [[Category: Catalysis]] | ||
| + | [[Category: Cross-coupling]] | ||
| + | [[Category: Heck reaction]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Metalloenzyme]] | ||
| + | [[Category: Palladium]] | ||
| + | [[Category: Protease]] | ||
Revision as of 13:51, 7 October 2015
Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase
| |||||||||||
