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4uco
From Proteopedia
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==Fragment bound to H.influenza NAD dependent DNA ligase== | ==Fragment bound to H.influenza NAD dependent DNA ligase== | ||
<StructureSection load='4uco' size='340' side='right' caption='[[4uco]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4uco' size='340' side='right' caption='[[4uco]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4uco]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UCO FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4uco]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UCO FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D41:7-AMINO-2-TERT-BUTYL-4-(1H-PYRROL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>D41</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D41:7-AMINO-2-TERT-BUTYL-4-(1H-PYRROL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>D41</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ucr|4ucr]], [[4ucs|4ucs]], [[4uct|4uct]], [[4ucu|4ucu]], [[4ucv|4ucv]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ucr|4ucr]], [[4ucs|4ucs]], [[4uct|4uct]], [[4ucu|4ucu]], [[4ucv|4ucv]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uco OCA], [http://pdbe.org/4uco PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uco RCSB], [http://www.ebi.ac.uk/pdbsum/4uco PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uco OCA], [http://pdbe.org/4uco PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uco RCSB], [http://www.ebi.ac.uk/pdbsum/4uco PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uco ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | [[http://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN]] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | ||
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| + | ==See Also== | ||
| + | *[[DNA ligase|DNA ligase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bacterium influenzae lehmann and neumann 1896]] | ||
[[Category: Boriack-Sjodin, P A]] | [[Category: Boriack-Sjodin, P A]] | ||
[[Category: Brassington, C]] | [[Category: Brassington, C]] | ||
Revision as of 06:40, 4 April 2018
Fragment bound to H.influenza NAD dependent DNA ligase
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Categories: Bacterium influenzae lehmann and neumann 1896 | Boriack-Sjodin, P A | Brassington, C | Carcanague, D | Embrey, K | Eyermann, C J | Giacobbe, R A | Gingipali, L | Gowravaram, M | Hale, M | Harang, J | Howard, T | Ioannidis, G | Jahic, H | Kutschke, A | Laganas, V A | Loch, J | Miller, M D | Murphy-Benenato, K E | Oguto, H | Otterbein, L | Patel, S J | Shapiro, A B | Ligase
