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5arc

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'''Unreleased structure'''
 
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The entry 5arc is ON HOLD until Paper Publication
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==Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase==
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<StructureSection load='5arc' size='340' side='right' caption='[[5arc]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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Authors: Sharma, M., Diaz-Rodriguez, A., Offen, W.A., Palm-Espling, M.E., Pordea, A., Wormald, M.R., Mcdonough, M., Davies, G.J., Davis, B.G.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5arc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ARC FirstGlance]. <br>
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Description: Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EI3:5-METHYL-2-(5-METHYLPYRIDIN-2-YL)PYRIDINE'>EI3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5aqe|5aqe]], [[5arb|5arb]], [[5ard|5ard]]</td></tr>
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[[Category: Wormald, M.R]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Subtilisin Subtilisin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.62 3.4.21.62] </span></td></tr>
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[[Category: Sharma, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5arc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5arc OCA], [http://pdbe.org/5arc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5arc RCSB], [http://www.ebi.ac.uk/pdbsum/5arc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5arc ProSAT]</span></td></tr>
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[[Category: Offen, W.A]]
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</table>
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[[Category: Pordea, A]]
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== Function ==
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[[Category: Davis, B.G]]
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[[http://www.uniprot.org/uniprot/SUBS_BACLE SUBS_BACLE]] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
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[[Category: Palm-Espling, M.E]]
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__TOC__
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[[Category: Davies, G.J]]
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</StructureSection>
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[[Category: Subtilisin]]
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[[Category: Davies, G J]]
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[[Category: Davis, B G]]
[[Category: Diaz-Rodriguez, A]]
[[Category: Diaz-Rodriguez, A]]
[[Category: Mcdonough, M]]
[[Category: Mcdonough, M]]
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[[Category: Offen, W A]]
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[[Category: Palm-Espling, M E]]
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[[Category: Pordea, A]]
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[[Category: Sharma, M]]
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[[Category: Wormald, M R]]
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[[Category: Catalysis]]
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[[Category: Cross-coupling]]
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[[Category: Heck reaction]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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[[Category: Palladium]]
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[[Category: Protease]]

Revision as of 15:26, 14 September 2016

Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase

5arc, resolution 1.10Å

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