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5e9v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of BRD9 bromodomain in complex with an indolizine ligand== | |
| + | <StructureSection load='5e9v' size='340' side='right' caption='[[5e9v]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5e9v]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E9V FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5L0:1-[1-(IMIDAZO[1,2-A]PYRIDIN-5-YL)-7-(MORPHOLIN-4-YL)INDOLIZIN-3-YL]ETHANONE'>5L0</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9v OCA], [http://pdbe.org/5e9v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e9v RCSB], [http://www.ebi.ac.uk/pdbsum/5e9v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e9v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BRD9_HUMAN BRD9_HUMAN]] May play a role in chromatin remodeling and regulation of transcription. | ||
| - | + | ==See Also== | |
| - | + | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: | + | [[Category: Bountra, C]] |
| + | [[Category: Brennan, P E]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A M]] | ||
[[Category: Fedorov, O]] | [[Category: Fedorov, O]] | ||
| - | [[Category: | + | [[Category: Hay, D A]] |
[[Category: Knapp, S]] | [[Category: Knapp, S]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| - | [[Category: | + | [[Category: Nunez-Alonso, G]] |
| - | [[Category: | + | [[Category: Picaud, S]] |
| - | [[Category: | + | [[Category: Schofield, C J]] |
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Tallant, C]] | [[Category: Tallant, C]] | ||
| + | [[Category: Bromodomain]] | ||
| + | [[Category: Chromatin regulation]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 17:00, 18 August 2017
Crystal structure of BRD9 bromodomain in complex with an indolizine ligand
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