Adenosine kinase
From Proteopedia
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AdK deficiency causes hypermethioninemia. Overexpression of AdK in the brain leads to decrease of adenosine and is believed as the main cause of epilepsy. | AdK deficiency causes hypermethioninemia. Overexpression of AdK in the brain leads to decrease of adenosine and is believed as the main cause of epilepsy. | ||
| + | == Structural highlights == | ||
| + | AdK consists of a large α/β domain with 9 β strands and 8 α helices and a small capping α/β domain with 5 β strands and 2 α helices. The active site is formed along the edge of the β sheet in the large domain. | ||
</StructureSection> | </StructureSection> | ||
Revision as of 09:07, 28 October 2015
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3D structures of adenosine kinase
Updated on 28-October-2015
