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Arginine kinase
From Proteopedia
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| - | <StructureSection load='1bg0' size='340' side='right' caption='Arginine kinase complex with arginine (stick model) and ADP (PDB code [[ | + | <StructureSection load='1bg0' size='340' side='right' caption='Arginine kinase complex with arginine, ADP, NO3- and Mg+2 ions (stick model) and ADP (PDB code [[1bg0]])' scene=''> |
== Function == | == Function == | ||
'''Arginine kinase''' (AK) is a phosphagen kinase which catalyzes the conversion of L-arginine and ATP to N-phospho-L-arginine and ADP. AK is part of arginine and proline metabolism. The phosphagen kinase reaction of AK is central to cellular energy homeostasis, i.e. maintenance of ATP level in invertebrates. Another phosphagen kinase found mostly in vertebrates is [[Creatine Kinase]] whose substrate is creatine. | '''Arginine kinase''' (AK) is a phosphagen kinase which catalyzes the conversion of L-arginine and ATP to N-phospho-L-arginine and ADP. AK is part of arginine and proline metabolism. The phosphagen kinase reaction of AK is central to cellular energy homeostasis, i.e. maintenance of ATP level in invertebrates. Another phosphagen kinase found mostly in vertebrates is [[Creatine Kinase]] whose substrate is creatine. | ||
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| - | == Disease == | ||
== Relevance == | == Relevance == | ||
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== Structural highlights == | == Structural highlights == | ||
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| + | The active site of AK is located between its N-terminal helical region and the larger C-terminal region. | ||
</StructureSection> | </StructureSection> | ||
Revision as of 11:42, 3 November 2015
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3D structures of arginine kinase
Updated on 03-November-2015
