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Aldose Reductase

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== Function ==
== Function ==
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[[Aldose Reductase]] (AldR) is an NADPH-dependent enzyme which reduces aldehydes and carbonyls. It reduces glucose to sorbitol in the glucose metabolism pathway.
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[[Aldose Reductase]] (AldR) is an NADPH-dependent enzyme which reduces aldehydes and carbonyls. It reduces glucose to sorbitol in the glucose metabolism pathway.<ref>PMID:1734286</ref>
== Disease ==
== Disease ==
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**[[2vdg]] – bAldR+NADP+butanol <br />
**[[2vdg]] – bAldR+NADP+butanol <br />
}}
}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:34, 3 December 2015

Human aldose reductase complex with cofactor NADP (PDB code 1ads)

Drag the structure with the mouse to rotate

3D Structures of Aldose Reductase

Updated on 03-December-2015

References

  1. Rondeau JM, Tete-Favier F, Podjarny A, Reymann JM, Barth P, Biellmann JF, Moras D. Novel NADPH-binding domain revealed by the crystal structure of aldose reductase. Nature. 1992 Jan 30;355(6359):469-72. PMID:1734286 doi:http://dx.doi.org/10.1038/355469a0

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