Bungarotoxin
From Proteopedia
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{{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin dimer [[2abx]] }} | {{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin dimer [[2abx]] }} | ||
| - | [[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]]. '''β-BGT''' binds to the presynaptic terminal causing release of acetylcholine. | + | [[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.<br /> |
| + | * '''α-BGT''' binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]].<br /> | ||
| + | * '''β-BGT''' binds to the presynaptic terminal causing release of acetylcholine.<br /> | ||
| + | * '''γ-BGT''' inhibits the binding of quinoclidinyl bezilate to the M2 muscarinic acetylcholine receptor. <br /> | ||
| + | * '''κ-BGT''' binds weakly to the nicotinic acetylcholine receptor. <br /> | ||
| + | For toxins in Proteopedia see [[Toxins]]. | ||
== 3D Structures of Bungarotoxin == | == 3D Structures of Bungarotoxin == | ||
Revision as of 07:33, 15 November 2015
Bungarotoxins. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait.
- α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in Alpha-bungarotoxin.
- β-BGT binds to the presynaptic terminal causing release of acetylcholine.
- γ-BGT inhibits the binding of quinoclidinyl bezilate to the M2 muscarinic acetylcholine receptor.
- κ-BGT binds weakly to the nicotinic acetylcholine receptor.
For toxins in Proteopedia see Toxins.
3D Structures of Bungarotoxin
Updated on 15-November-2015
