Calcium/Calmodulin-dependent protein kinase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
{{STRUCTURE_3mfr| PDB=3mfr | SIZE=400| SCENE=CaMKc/Cv/1 |right|CAPTION=Ca2+/Calmodulin dependent protein kinase complex with phosphoaminophosphonic acid-adenylate ester, [[3mfr]] }}
{{STRUCTURE_3mfr| PDB=3mfr | SIZE=400| SCENE=CaMKc/Cv/1 |right|CAPTION=Ca2+/Calmodulin dependent protein kinase complex with phosphoaminophosphonic acid-adenylate ester, [[3mfr]] }}
 +
__TOC__
 +
== Function ==
-
[[Ca2+/Calmodulin dependent protein kinase]] (CaMK) phosphorylates Ser and Thr. It is regulated by Ca<sup>2+</sup>/[[Calmodulin]] (CaM). It contains an N-terminal catalytic domain, regulatory domain (CBD) and association domain (ASD). CaMKI is a specialized CaM kinase while CaMKII is multifunctional kinase. '''CASK''' is a membrane associated CaMK. '''DAPK''' is a death-associated CaMK which protects cells from some programmed cell death. It contains a regulatory (RD) and autoinhibitory (AD) domains.
+
[[Ca2+/Calmodulin dependent protein kinase]] (CaMK) phosphorylates Ser and Thr. <br />
 +
*'''CaMKI''' is a specialized CaM kinase.<br />
 +
*'''CaMKII''' is multifunctional kinase. <br />
 +
*'''CASK''' is a membrane associated CaMK.<br />
 +
*'''DAPK''' is a death-associated CaMK which protects cells from some programmed cell death.
 +
 
 +
== Structural highlights ==
 +
 
 +
CAMK contains an N-terminal catalytic domain, regulatory domain (CBD) and association domain (ASD). DAPK contains a regulatory (RD) and autoinhibitory (AD) domains.
== 3D Structures of Ca<sup>2+</sup>/Calmodulin dependent protein kinase ==
== 3D Structures of Ca<sup>2+</sup>/Calmodulin dependent protein kinase ==

Revision as of 09:41, 15 November 2015

Template:STRUCTURE 3mfr

Contents

Function

Ca2+/Calmodulin dependent protein kinase (CaMK) phosphorylates Ser and Thr.

  • CaMKI is a specialized CaM kinase.
  • CaMKII is multifunctional kinase.
  • CASK is a membrane associated CaMK.
  • DAPK is a death-associated CaMK which protects cells from some programmed cell death.

Structural highlights

CAMK contains an N-terminal catalytic domain, regulatory domain (CBD) and association domain (ASD). DAPK contains a regulatory (RD) and autoinhibitory (AD) domains.

3D Structures of Ca2+/Calmodulin dependent protein kinase

Updated on 15-November-2015

See also

Calcium-dependent protein kinase, a member of the CaM kinase family

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Alice Harmon, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/Calcium/Calmodulin-dependent_protein_kinase"
Personal tools