Carbamoyl phosphate synthetase
From Proteopedia
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| - | + | <StructureSection load='1a9x' size='450' side='right' scene='' caption='E. coli carbamoyl phosphate synthetase large chains (grey, pink, magenta, gold) and small chains (green, yellow, cyan, red) complex with ADP, phosphate and ornithine, [[1a9x]]'> | |
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== Function == | == Function == | ||
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CPS I and II are composed of 2 subunits. The large subunit contain active sites which bind nucleotides and other effectors. The small subunit catalyzes the hydrolysis of glutamine to glutamate and NH3. The small subunit active site contains an active Cys residue. CPS I contains a methylglyoxal synthetase (MGS) domain which binds ornithine. | CPS I and II are composed of 2 subunits. The large subunit contain active sites which bind nucleotides and other effectors. The small subunit catalyzes the hydrolysis of glutamine to glutamate and NH3. The small subunit active site contains an active Cys residue. CPS I contains a methylglyoxal synthetase (MGS) domain which binds ornithine. | ||
| - | + | </StructureSection> | |
==3D structures of carbamoyl phosphate synthetase== | ==3D structures of carbamoyl phosphate synthetase== | ||
Revision as of 10:51, 19 November 2015
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3D structures of carbamoyl phosphate synthetase
Updated on 19-November-2015
2yvq – CPS I MGS domain - human
1jdb - EcCPS + phosphate + glutamine + ADP – Escherichia coli
1a9x, 1cs0 - EcCPS + phosphate + ornithine + ADP
1c30, 1m6v - EcCPS (mutant) + phosphate + ornithine + ADP
1bxr - EcCPS + ornithine + AMPPNP
1ce8 - EcCPS + phosphate + ornithine + inosinic acid + ADP
1c3o - EcCPS (mutant) + phosphate + ornithine + glutamine + ADP
1kee - EcCPS + phosphate + ornithine + acivicin + ADP
1t36 - EcCPS (mutant) + phosphate + ornithine + UMP + ADP
