Casein kinase

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**[[2chl]] - hCK1-γ3<br />
**[[2chl]] - hCK1-γ3<br />
**[[2cmw]] – hCK1-γ1 + inhibitor<br />
**[[2cmw]] – hCK1-γ1 + inhibitor<br />
-
**[[2izr]], [[2izs]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]] - hCK1-γ3 + inhibitor<br />
+
**[[2izr]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]] - hCK1-γ3 + inhibitor<br />
**[[3uys]] – hCK1-δ<br />
**[[3uys]] – hCK1-δ<br />
**[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br />
**[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br />

Revision as of 10:24, 19 November 2015

Template:STRUCTURE 3mb6

Function

Casein kinase (CK) is a protein kinase which functions as regulator of signal transduction.

  • CK1 is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε.
  • CK2 functions in cell cycle control, DNA repair and circadian rhythm regulation.

Structural highlights

CK2 is a tetramer with a pair of 2 subunits – the α subunit is the catalytic one and the β subunit is the regulatory one.

3D Structures of casein kinase

Updated on 19-November-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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