Casein kinase
From Proteopedia
(Difference between revisions)
Line 21: | Line 21: | ||
**[[2chl]] - hCK1-γ3<br /> | **[[2chl]] - hCK1-γ3<br /> | ||
**[[2cmw]] – hCK1-γ1 + inhibitor<br /> | **[[2cmw]] – hCK1-γ1 + inhibitor<br /> | ||
- | **[[2izr | + | **[[2izr]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]] - hCK1-γ3 + inhibitor<br /> |
**[[3uys]] – hCK1-δ<br /> | **[[3uys]] – hCK1-δ<br /> | ||
**[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br /> | **[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]] – hCK1-δ + inhibitor<br /> |
Revision as of 10:24, 19 November 2015
Function
Casein kinase (CK) is a protein kinase which functions as regulator of signal transduction.
- CK1 is a serine/threonine kinase with several members: α, β1, γ1, γ2, γ3, δ and ε.
- CK2 functions in cell cycle control, DNA repair and circadian rhythm regulation.
Structural highlights
CK2 is a tetramer with a pair of 2 subunits – the α subunit is the catalytic one and the β subunit is the regulatory one.
3D Structures of casein kinase
Updated on 19-November-2015