Catabolite gene activator protein
From Proteopedia
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| - | <StructureSection load='1o3r' size='450' side='right' scene='54/543372/Cv/1' caption='Catabolite gene activator protein complex with cAMP | + | <StructureSection load='1o3r' size='450' side='right' scene='54/543372/Cv/1' caption='Catabolite gene activator protein complex with cAMP and DNA [[1o3r]]'> |
'''Catabolite gene activator protein''' (CAP) is a DNA-binding protein involved in the transcription of several genes including those involved in the metabolism of sugar. CAP can activate or repress transcription initiation upon binding of cAMP. The cAMP-CAP complex binds to promoters on the DNA. The structure contains a ligand-binding domain (LBD) at the N-terminal and DNA-binding domain (DBD) at the C-terminal. Two cAMP molecules bind to the dimeric CAP. When the amount of glucose transported into the cell is low, cAMP level rises and the cAMP-CAP complex causes increase of transcription of glucose metabolism genes. | '''Catabolite gene activator protein''' (CAP) is a DNA-binding protein involved in the transcription of several genes including those involved in the metabolism of sugar. CAP can activate or repress transcription initiation upon binding of cAMP. The cAMP-CAP complex binds to promoters on the DNA. The structure contains a ligand-binding domain (LBD) at the N-terminal and DNA-binding domain (DBD) at the C-terminal. Two cAMP molecules bind to the dimeric CAP. When the amount of glucose transported into the cell is low, cAMP level rises and the cAMP-CAP complex causes increase of transcription of glucose metabolism genes. | ||
| + | *<scene name='54/543372/Cv/2'>Catabolite gene activator protein complex with cAMP and DNA</scene> ([[1o3r]]). | ||
</StructureSection> | </StructureSection> | ||
== 3D Structures of catabolite gene activator protein == | == 3D Structures of catabolite gene activator protein == | ||
Revision as of 12:29, 22 November 2015
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3D Structures of catabolite gene activator protein
Updated on 22-November-2015
