CD1
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules. | '''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules. | ||
| - | *<scene name='55/551229/Cv/2'> | + | *<scene name='55/551229/Cv/2'>Mouse CD1 extracellular domain containing β-microglobulin complex with glycolipid</scene>(PDB entry [[3ilp]]).<ref>PMID:20080535</ref> |
</StructureSection> | </StructureSection> | ||
| Line 33: | Line 33: | ||
**[[3ubx]] – mCD1 extracellular domain + β-microglobulin + glycolipid+ antibody <BR /> | **[[3ubx]] – mCD1 extracellular domain + β-microglobulin + glycolipid+ antibody <BR /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||
Revision as of 12:07, 23 November 2015
| |||||||||||
3D Structures of CD1
Updated on 23-November-2015
