CD2-associated protein
From Proteopedia
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<StructureSection load='2j6o' size='450' side='right' caption='Structure of human CD2AP SH3 domain 1 (green) complex with E3 ubiquitin ligase peptide (deeppink) (PDB entry [[2j6o]])' scene='56/569738/Cv/1'> | <StructureSection load='2j6o' size='450' side='right' caption='Structure of human CD2AP SH3 domain 1 (green) complex with E3 ubiquitin ligase peptide (deeppink) (PDB entry [[2j6o]])' scene='56/569738/Cv/1'> | ||
| - | '''CD2-associated protein''' (CD2AP) called also '''CMS''', is a scaffolding protein which regulates actin cytoskeleton. CD2AP SH3 domain interacts with actin and a variety of membrane proteins. CD2AP contains in its N-terminal 3 SH3 domains followed by a proline-rich region. | + | '''CD2-associated protein''' (CD2AP) called also '''CMS''', is a scaffolding protein which regulates actin cytoskeleton. CD2AP SH3 domain interacts with actin and a variety of membrane proteins. CD2AP contains in its N-terminal 3 SH3 domains followed by a proline-rich region.<ref>PMID:12354621</ref><ref>PMID:17020880</ref> |
</StructureSection> | </StructureSection> | ||
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**[[3lk4]], [[3aa6]] – hCD2AP + CapZ<br /> | **[[3lk4]], [[3aa6]] – hCD2AP + CapZ<br /> | ||
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| + | == References == | ||
| + | <references/> | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||
Revision as of 12:35, 23 November 2015
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3D structures of CD2-associated protein
Updated on 23-November-2015
References
- ↑ Dikic I. CIN85/CMS family of adaptor molecules. FEBS Lett. 2002 Oct 2;529(1):110-5. PMID:12354621
- ↑ Moncalian G, Cardenes N, Deribe YL, Spinola-Amilibia M, Dikic I, Bravo J. Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain. J Biol Chem. 2006 Dec 15;281(50):38845-53. Epub 2006 Oct 3. PMID:17020880 doi:10.1074/jbc.M606411200
