CD59

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'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9.
'''CD59''' ('''Cluster of Differentiation 59''') is a protein which attaches to host cells via a GPI anchor. CD59 can prevent the formation of complement membrane attack complex via binding to complement C8 or C9.
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== Relevance ==
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HIV, vaccinia and cytomegalovirus incorporate human CD59 into their envelope thus preventing their lysis by complement.
== Disease ==
== Disease ==

Revision as of 11:58, 24 November 2015

Structure of human CD59 extracellular domain (green and yellow) complex with intermedilysin (grey and pink) (PDB entry 4bik)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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