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4ufz
From Proteopedia
(Difference between revisions)
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==Synthesis of Novel NAD Dependant DNA Ligase Inhibitors via Negishi Cross-Coupling: Development of SAR and Resistance Studies== | ==Synthesis of Novel NAD Dependant DNA Ligase Inhibitors via Negishi Cross-Coupling: Development of SAR and Resistance Studies== | ||
<StructureSection load='4ufz' size='340' side='right' caption='[[4ufz]], [[Resolution|resolution]] 2.33Å' scene=''> | <StructureSection load='4ufz' size='340' side='right' caption='[[4ufz]], [[Resolution|resolution]] 2.33Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IA7:5,7-BIS(AZANYL)-2-TERT-BUTYL-4-(1,3-THIAZOL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBONITRILE'>IA7</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IA7:5,7-BIS(AZANYL)-2-TERT-BUTYL-4-(1,3-THIAZOL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBONITRILE'>IA7</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_ligase_(NAD(+)) DNA ligase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.5.1.2 6.5.1.2] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ufz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ufz OCA], [http://pdbe.org/4ufz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ufz RCSB], [http://www.ebi.ac.uk/pdbsum/4ufz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ufz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ufz OCA], [http://pdbe.org/4ufz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ufz RCSB], [http://www.ebi.ac.uk/pdbsum/4ufz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ufz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ufz" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ufz" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[DNA ligase|DNA ligase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 17:12, 18 August 2017
Synthesis of Novel NAD Dependant DNA Ligase Inhibitors via Negishi Cross-Coupling: Development of SAR and Resistance Studies
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