4xjv
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of human thioesterase 2== |
| - | + | <StructureSection load='4xjv' size='340' side='right' caption='[[4xjv]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xjv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oleoyl-[acyl-carrier-protein]_hydrolase Oleoyl-[acyl-carrier-protein] hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.14 3.1.2.14] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjv OCA], [http://pdbe.org/4xjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjv RCSB], [http://www.ebi.ac.uk/pdbsum/4xjv PDBsum]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Lowther, W | + | == Function == |
| - | [[Category: Ritchie, M | + | [[http://www.uniprot.org/uniprot/SAST_HUMAN SAST_HUMAN]] In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity). |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Kridel, S J]] | ||
| + | [[Category: Lowther, W T]] | ||
| + | [[Category: Ritchie, M K]] | ||
| + | [[Category: Closed conformation]] | ||
| + | [[Category: Fatty acid synthase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lipid metabolism]] | ||
Revision as of 13:54, 16 December 2015
Crystal structure of human thioesterase 2
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