4xo8
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Crystal structure of the FimH lectin domain from E.coli K12 in complex with heptyl alpha-D-mannopyrannoside== |
| - | + | <StructureSection load='4xo8' size='340' side='right' caption='[[4xo8]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xo8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XO8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KGM:HEPTYL+ALPHA-D-MANNOPYRANNOSIDE'>KGM</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xo8 OCA], [http://pdbe.org/4xo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xo8 RCSB], [http://www.ebi.ac.uk/pdbsum/4xo8 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. |
| - | [ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
[[Category: Eras, J]] | [[Category: Eras, J]] | ||
| - | [[Category: Jakob, R | + | [[Category: Ernst, B]] |
| + | [[Category: Glockshuber, R]] | ||
| + | [[Category: Jakob, R P]] | ||
| + | [[Category: Maier, T]] | ||
[[Category: Navarra, G]] | [[Category: Navarra, G]] | ||
| + | [[Category: Bacterial adhesin]] | ||
| + | [[Category: Catch bond]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Mannose]] | ||
| + | [[Category: Type i pilus]] | ||
| + | [[Category: Upec]] | ||
| + | [[Category: Uti]] | ||
Revision as of 02:27, 28 January 2016
Crystal structure of the FimH lectin domain from E.coli K12 in complex with heptyl alpha-D-mannopyrannoside
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Categories: Eras, J | Ernst, B | Glockshuber, R | Jakob, R P | Maier, T | Navarra, G | Bacterial adhesin | Catch bond | Cell adhesion | Lectin | Mannose | Type i pilus | Upec | Uti
