This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4ym9
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102== | |
| - | + | <StructureSection load='4ym9' size='340' side='right' caption='[[4ym9]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YM9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ym9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ym9 OCA], [http://pdbe.org/4ym9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ym9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ym9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ym9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Pancreatic elastase]] | ||
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Archer, M]] | ||
| + | [[Category: Brito, J A]] | ||
| + | [[Category: Hofbauer, S]] | ||
| + | [[Category: Moreira, R]] | ||
| + | [[Category: Mulchande, J]] | ||
[[Category: Nogly, P]] | [[Category: Nogly, P]] | ||
| - | [[Category: Brito, J.A]] | ||
| - | [[Category: Mulchande, J]] | ||
| - | [[Category: Moreira, R]] | ||
[[Category: Pessanha, M]] | [[Category: Pessanha, M]] | ||
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | [[Category: | + | [[Category: Inhibitor]] |
| + | [[Category: Porcine pancreatic elastase]] | ||
Revision as of 10:13, 13 July 2016
Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102
| |||||||||||
