5ed6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==crystal structure of human Hint1 H114A mutant complexing with ATP== | |
| - | + | <StructureSection load='5ed6' size='340' side='right' caption='[[5ed6]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ed6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ED6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ED6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ecb|5ecb]], [[5ecz|5ecz]], [[5ed3|5ed3]], [[5ed5|5ed5]], [[5ede|5ede]], [[5efl|5efl]], [[5efp|5efp]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ed6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ed6 OCA], [http://pdbe.org/5ed6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ed6 RCSB], [http://www.ebi.ac.uk/pdbsum/5ed6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ed6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN]] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fang, P]] | ||
[[Category: Guo, M]] | [[Category: Guo, M]] | ||
| - | [[Category: Fang, P]] | ||
[[Category: Wang, J]] | [[Category: Wang, J]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nucleotide binding]] | ||
| + | [[Category: Regulation of transcription]] | ||
| + | [[Category: Signal transduction]] | ||
Revision as of 23:38, 25 January 2017
crystal structure of human Hint1 H114A mutant complexing with ATP
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