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5fn0
From Proteopedia
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| - | ''' | + | ==Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180== |
| - | + | <StructureSection load='5fn0' size='340' side='right' caption='[[5fn0]], [[Resolution|resolution]] 3.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5fn0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FN0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=JHY:3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC+ACID'>JHY</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Kynurenine_3-monooxygenase Kynurenine 3-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.9 1.14.13.9] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fn0 OCA], [http://pdbe.org/5fn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/5fn0 PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [[http://www.uniprot.org/uniprot/KMO_PSEFL KMO_PSEFL]] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Probably required for the synthesis of quinolinic acid and the siderophore quinolobactin. | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Kynurenine 3-monooxygenase]] | |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Ancellin, N]] | [[Category: Ancellin, N]] | ||
| - | [[Category: | + | [[Category: Baily, J E]] |
| - | [[Category: | + | [[Category: Beaufils, B]] |
[[Category: Beneton, V]] | [[Category: Beneton, V]] | ||
| + | [[Category: Binnie, M]] | ||
| + | [[Category: Garden, O J]] | ||
[[Category: Haslam, C]] | [[Category: Haslam, C]] | ||
| - | [[Category: Uings, I]] | ||
| - | [[Category: Wilkinson, M]] | ||
| - | [[Category: Hutchinson, J.P]] | ||
| - | [[Category: Liddle, J]] | ||
| - | [[Category: Walker, A]] | ||
| - | [[Category: Webster, S.P]] | ||
[[Category: Holmes, D]] | [[Category: Holmes, D]] | ||
| - | [[Category: | + | [[Category: Homer, N Z.M]] |
| - | [[Category: Howie, S | + | [[Category: Howie, S E.M]] |
| - | [[Category: | + | [[Category: Hughes, J]] |
| - | [[Category: | + | [[Category: Hutchinson, J P]] |
| - | [[Category: | + | [[Category: Iredale, J P]] |
| + | [[Category: Liddle, J]] | ||
| + | [[Category: McBride, A]] | ||
[[Category: Mirguet, O]] | [[Category: Mirguet, O]] | ||
| + | [[Category: Mole, D J]] | ||
| + | [[Category: Mowat, C G]] | ||
| + | [[Category: Rowland, P]] | ||
| + | [[Category: Sharp, M G.F]] | ||
| + | [[Category: Trottet, L]] | ||
| + | [[Category: Uings, I]] | ||
| + | [[Category: Walker, A]] | ||
| + | [[Category: Webster, S P]] | ||
| + | [[Category: Wilkinson, M]] | ||
| + | [[Category: Wilson, K]] | ||
| + | [[Category: Zheng, X]] | ||
| + | [[Category: Kmo]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 20:37, 13 January 2016
Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180
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Categories: Kynurenine 3-monooxygenase | Ancellin, N | Baily, J E | Beaufils, B | Beneton, V | Binnie, M | Garden, O J | Haslam, C | Holmes, D | Homer, N Z.M | Howie, S E.M | Hughes, J | Hutchinson, J P | Iredale, J P | Liddle, J | McBride, A | Mirguet, O | Mole, D J | Mowat, C G | Rowland, P | Sharp, M G.F | Trottet, L | Uings, I | Walker, A | Webster, S P | Wilkinson, M | Wilson, K | Zheng, X | Kmo | Oxidoreductase
