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5ec3
From Proteopedia
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==Structural insight into the catalyitc mechanism of human 4-Hydroxyphenylpyruvate dioxygenase== | ==Structural insight into the catalyitc mechanism of human 4-Hydroxyphenylpyruvate dioxygenase== | ||
| - | <StructureSection load='5ec3' size='340' side='right' caption='[[5ec3]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='5ec3' size='340' side='right'caption='[[5ec3]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ec3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EC3 OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5ec3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EC3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EC3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3isq|3isq]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3isq|3isq]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HPD, PPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxyphenylpyruvate_dioxygenase 4-hydroxyphenylpyruvate dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.27 1.13.11.27] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxyphenylpyruvate_dioxygenase 4-hydroxyphenylpyruvate dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.27 1.13.11.27] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ec3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ec3 OCA], [http://pdbe.org/5ec3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ec3 RCSB], [http://www.ebi.ac.uk/pdbsum/5ec3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ec3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/HPPD_HUMAN HPPD_HUMAN]] Key enzyme in the degradation of tyrosine. | [[http://www.uniprot.org/uniprot/HPPD_HUMAN HPPD_HUMAN]] Key enzyme in the degradation of tyrosine. | ||
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| + | ==See Also== | ||
| + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 4-hydroxyphenylpyruvate dioxygenase]] | [[Category: 4-hydroxyphenylpyruvate dioxygenase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Yang, G F]] | [[Category: Yang, G F]] | ||
[[Category: Yang, W C]] | [[Category: Yang, W C]] | ||
[[Category: Drug discovery]] | [[Category: Drug discovery]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 06:52, 22 April 2020
Structural insight into the catalyitc mechanism of human 4-Hydroxyphenylpyruvate dioxygenase
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