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Aminomutase
From Proteopedia
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<StructureSection load='2ohy' size='340' side='right' caption='Tyrosine aminomutase complex with peptide-derived chromophore cofactor (PDB code [[2ohy]])' scene='71/715468/Cv/1'> | <StructureSection load='2ohy' size='340' side='right' caption='Tyrosine aminomutase complex with peptide-derived chromophore cofactor (PDB code [[2ohy]])' scene='71/715468/Cv/1'> | ||
| - | '''Aminomutases''' catalyze the exchange of hydrogen atom and an amine substituent on a neighboring carbon atom. | + | '''Aminomutases''' catalyze the exchange of hydrogen atom and an amine substituent on a neighboring carbon atom.<ref>PMID:17516659</ref> |
*'''Phenylalanine aminomutase''' (PAM) catalyzes the reversible conversion of L-phenylalanine to ammonia and trans-cinnamic acid. Ala-Ser-Gly derived chromophore is a cofactor. | *'''Phenylalanine aminomutase''' (PAM) catalyzes the reversible conversion of L-phenylalanine to ammonia and trans-cinnamic acid. Ala-Ser-Gly derived chromophore is a cofactor. | ||
Revision as of 11:20, 3 December 2015
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3D structures of aminomutase
Updated on 03-December-2015
References
- ↑ Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway. Biochemistry. 2007 Jun 19;46(24):7205-14. Epub 2007 May 22. PMID:17516659 doi:10.1021/bi7003685
