2mx2
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==UBX-L domain of VCIP135== | |
- | + | <StructureSection load='2mx2' size='340' side='right' caption='[[2mx2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2mx2]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MX2 FirstGlance]. <br> | |
- | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr> | |
- | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mx2 OCA], [http://pdbe.org/2mx2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mx2 RCSB], [http://www.ebi.ac.uk/pdbsum/2mx2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mx2 ProSAT]</span></td></tr> |
- | [[ | + | </table> |
- | [[Category: | + | == Function == |
+ | [[http://www.uniprot.org/uniprot/VCIP1_RAT VCIP1_RAT]] Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.<ref>PMID:12473691</ref> <ref>PMID:15037600</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Ubiquitinyl hydrolase 1]] | ||
[[Category: Hrioaki, H]] | [[Category: Hrioaki, H]] | ||
+ | [[Category: Igarashi, R]] | ||
[[Category: Iwazu, T]] | [[Category: Iwazu, T]] | ||
+ | [[Category: Murayama, S]] | ||
+ | [[Category: Shirakawa, M]] | ||
[[Category: Tochio, H]] | [[Category: Tochio, H]] | ||
- | [[Category: | + | [[Category: Golgi]] |
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Mitosis]] | ||
+ | [[Category: Ubx domain]] |
Revision as of 11:39, 14 July 2016
UBX-L domain of VCIP135
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Categories: Ubiquitinyl hydrolase 1 | Hrioaki, H | Igarashi, R | Iwazu, T | Murayama, S | Shirakawa, M | Tochio, H | Golgi | Hydrolase | Mitosis | Ubx domain