5esv
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.== | |
| - | + | <StructureSection load='5esv' size='340' side='right' caption='[[5esv]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5esv]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ESV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ESV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5esv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5esv OCA], [http://pdbe.org/5esv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5esv RCSB], [http://www.ebi.ac.uk/pdbsum/5esv PDBsum]</span></td></tr> | |
| - | + | </table> | |
| - | [[ | + | == Function == |
| - | [[ | + | [[http://www.uniprot.org/uniprot/ISPF_HAEIN ISPF_HAEIN]] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107] |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Gorman, J]] | [[Category: Gorman, J]] | ||
| + | [[Category: Kwong, P D]] | ||
| + | [[Category: Yang, M]] | ||
| + | [[Category: Cap256]] | ||
| + | [[Category: Ch0219]] | ||
| + | [[Category: Chavi]] | ||
| + | [[Category: Env]] | ||
| + | [[Category: Hiv-1]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Scaffold]] | ||
| + | [[Category: V1v2]] | ||
Revision as of 13:58, 16 December 2015
Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.
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Categories: Gorman, J | Kwong, P D | Yang, M | Cap256 | Ch0219 | Chavi | Env | Hiv-1 | Immune system | Scaffold | V1v2
