1agq
From Proteopedia
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[[Image:1agq.gif|left|200px]] | [[Image:1agq.gif|left|200px]] | ||
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'''GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT''' | '''GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT''' | ||
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[[Category: Eigenbrot, C.]] | [[Category: Eigenbrot, C.]] | ||
[[Category: Gerber, N.]] | [[Category: Gerber, N.]] | ||
- | [[Category: | + | [[Category: Cystine knot]] |
- | [[Category: | + | [[Category: Growth factor]] |
- | [[Category: | + | [[Category: Neurotrophic factor]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:14:54 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 07:14, 2 May 2008
GLIAL CELL-DERIVED NEUROTROPHIC FACTOR FROM RAT
Overview
The crystal structure of glial cell-derived neurotrophic factor (GDNF) reveals two independent copies of the dimer that differ significantly through a hinge bending at the central, disulphide-rich region. GDNF is compared with other members of the TGF-beta family, and potential receptor binding surfaces are identified.
About this Structure
1AGQ is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding., Eigenbrot C, Gerber N, Nat Struct Biol. 1997 Jun;4(6):435-8. PMID:9187648 Page seeded by OCA on Fri May 2 10:14:54 2008