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ATP-citrate synthase

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== Structural highlights ==
== Structural highlights ==
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Crystal structures have shown that tartrate and citrate bind to ACS in the same binding site. <scene name='47/477091/Cv/2'>Binding site with tartrate</scene> of ATP-citrate synthase with <scene name='47/477091/Cv/3'>ADP, Mg+2 ions</scene> , [[3pff]]. <ref>PMID:22102020</ref>
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Crystal structures have shown that tartrate and citrate bind to ACS in the same binding site. <scene name='47/477091/Cv/2'>Binding site of tartrate</scene> of ATP-citrate synthase. <scene name='47/477091/Cv/3'>Binding site of ADP and Mg+2 ions</scene> , [[3pff]]. <ref>PMID:22102020</ref>
</StructureSection>
</StructureSection>

Revision as of 08:56, 3 December 2015

ATP-citrate synthase complex with ADP (stick model), tartrate and Mg+2 ions (green), 3pff

Drag the structure with the mouse to rotate

3D Structures of ATP-citrate synthase

Updated on 03-December-2015

3mwd – hACS + citrate – human
3mwe – hACS + tartrate
3pff - hACS + tartrate + ADP

References

  1. ↑ Sun T, Hayakawa K, Fraser ME. ADP-Mg2+ bound to the ATP-grasp domain of ATP-citrate lyase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1168-72., Epub 2011 Sep 24. PMID:22102020 doi:10.1107/S1744309111028363

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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