3-phosphoinositide-dependent protein kinase 1
From Proteopedia
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== Function == | == Function == | ||
| - | '''3-phosphoinositide-dependent protein kinase 1''' (Pdk1) activates many other kinases. Pdk1 main effector is protein kinase B (Akt). <scene name='54/542348/Cv/2'>Serine (Ser241 in human) is the Pdk1 phosphorylated residue (PSer)</scene>. Pdk1 is important in signaling pathways activated by growth factors and hormones. It interacts with membrane phospholipids. | + | '''3-phosphoinositide-dependent protein kinase 1''' (Pdk1) activates many other kinases. Pdk1 main effector is protein kinase B (Akt). <scene name='54/542348/Cv/2'>Serine (Ser241 in human) is the Pdk1 phosphorylated residue (PSer)</scene>. Pdk1 is important in signaling pathways activated by growth factors and hormones. It interacts with membrane phospholipids. <ref>PMID:15209375</ref> |
== Disease == | == Disease == | ||
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== References == | == References == | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:40, 3 December 2015
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3D Structures of Pdk1
Updated on 03-December-2015
References
- ↑ Mora A, Komander D, van Aalten DM, Alessi DR. PDK1, the master regulator of AGC kinase signal transduction. Semin Cell Dev Biol. 2004 Apr;15(2):161-70. PMID:15209375
