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Antithrombin

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== Relevance ==
== Relevance ==
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AT activity is enhanced upon <scene name='46/466527/Cv/2'>binding to the anticoagulant drug heparin</scene>.
+
AT activity is enhanced upon <scene name='46/466527/Cv/3'>binding to the anticoagulant drug heparin</scene>.
==Structural highlights==
==Structural highlights==

Revision as of 09:23, 8 December 2015

Glycosylated human antithrombin III complex with heparin (in green) (PDB code 3evj)

Drag the structure with the mouse to rotate

3D structures of antithrombin

Updated on 08-December-2015

References

  1. ↑ Li W, Johnson DJ, Esmon CT, Huntington JA. Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:15311269 doi:10.1038/nsmb811

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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