Circadian clock protein
From Proteopedia
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<StructureSection load='1r8j' size='350' side='right' caption='Circadian clock protein KaiA (PDB entry [[1r8j]])' scene=''> | <StructureSection load='1r8j' size='350' side='right' caption='Circadian clock protein KaiA (PDB entry [[1r8j]])' scene=''> | ||
| - | '''Circadian clock proteins''' measure out the 24 hour circadian rhythm. In cyanobacteria protein KaiA stimulates KaiC which adds phosphate groups to itself. Then KaiC binds to KaiB which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly. KaiB disconnects allowing KaiA to start the cycle again.<ref>PMID:11687489</ref> For details of KaiC see [[Circadian Clock Protein KaiC]]. | + | '''Circadian clock proteins''' measure out the 24 hour circadian rhythm. In cyanobacteria protein KaiA<ref>PMID:15007067</ref> stimulates KaiC<ref>PMID:15304218</ref> which adds phosphate groups to itself. Then KaiC binds to KaiB<ref>PMID:15716247</ref> which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly. KaiB disconnects allowing KaiA to start the cycle again.<ref>PMID:11687489</ref> For details of KaiC see [[Circadian Clock Protein KaiC]]. |
</StructureSection> | </StructureSection> | ||
== 3D Structures of circadian clock protein == | == 3D Structures of circadian clock protein == | ||
Revision as of 10:59, 8 December 2015
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3D Structures of circadian clock protein
Updated on 08-December-2015
References
- ↑ Ye S, Vakonakis I, Ioerger TR, LiWang AC, Sacchettini JC. Crystal structure of circadian clock protein KaiA from Synechococcus elongatus. J Biol Chem. 2004 May 7;279(19):20511-8. Epub 2004 Mar 8. PMID:15007067 doi:10.1074/jbc.M400077200
- ↑ Pattanayek R, Wang J, Mori T, Xu Y, Johnson CH, Egli M. Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. Mol Cell. 2004 Aug 13;15(3):375-88. PMID:15304218 doi:10.1016/j.molcel.2004.07.013
- ↑ . PMID:15716247
- ↑ Harmer SL, Panda S, Kay SA. Molecular bases of circadian rhythms. Annu Rev Cell Dev Biol. 2001;17:215-53. PMID:11687489 doi:http://dx.doi.org/10.1146/annurev.cellbio.17.1.215
